Methadone As Normal Medicine

SUMMARY

Methadone prescribing increased tenfold in the last four years in

Belgium. This has been made possible through involvement of general

practitioners in methadone treatment. Drug overdoses, crime and even

presence of methadone on the black market have decreased at the same

time.

Introduction

During the last four years, methadone consumption in Belgium

increased tenfold (From 6 kg/year in 1990 to 58 kg/year in 1994). This

fact may seem insignificant because it concerns a country with a

population no higher than that of New York City and whose precise

geographic location may not be known to everyone. However the Belgian

experience might demonstrate that it is possible to overcome certain

limitations of methadone treatment as it is generally

practiced.

Legal Confrontation

Methadone has been available with a prescription in pharmacies since

the 1970’s. But physicians who began to prescribe it to addicts at the

beginning of the 1980’s, when the heroin epidemic was worsening, were

often subjected to disciplinary sanctions by the Belgian Medical

Association and sentenced by courts of justice.

At the beginning of the 1990’s a group of physicians, including

myself, requested that the Supreme Court revoke the Medical Association’s

regulations permitting the indictment of physicians prescribing methadone

and other substitution treatments. This request was granted. Subsequently,

the regional authorities of the French speaking part of Belgium began to

encourage physicians to treat opiate addicts with methadone. The

authorities became aware of drug addiction’s impact on criminality and on

the AIDS epidemic. They knew that it would be impossible to extend rapidly

the number of methadone clinics and they also wanted to avoid stigmatizing

heroin addicts. To encourage the treatment of addicts in normal settings,

they allocated funds for training sessions for general practitioners on

treatment of drug addiction.

Consensus Conference

Another measure which permitted a rapid expansion of methadone

treatment was the organization of a Consensus Conference on Methadone

Treatment by our Minister of Health. The conclusions of the Consensus

Conference were sent to every doctor in the country, as new guidelines for

methadone treatment. They stated the following points:

  • Methadone is an effective medication for the treatment of heroin

    addiction.

  • Methadone reduces heroin consumption and injection, reduces

    mortality related to heroin addiction, reduces the risk of infection

    with HIV as well as hepatitis B and C, improves therapeutic compliance

    of HIV-positive drug addicts, facilitates detection of illness and

    health education strategies and is associated with an improvement in

    socio- professional aptitude and a reduction in delinquency.

  • Prolonged treatment with proper doses of methadone is medically

    safe. At present, methadone has not been shown to be toxic for any

    organ.

  • There is no scientific reason to limit the overall number of

    heroin addicts admitted for methadone treatment.

  • Availability of methadone treatment should be increased to

    respond to the need for such treatment, including by private

    practitioners.

  • Psycho-social support is not compulsory and should be adapted to

    the individual needs of patients.

These conclusions are in no way revolutionary on the scientific

level, but as official guidelines for methadone treatment, they represent

a significant innovation, compared to what happens in a lot of countries.

Methadone is now dealt with as an ordinary medication. Its effectiveness

is recognized without ambiguity. No longer is it considered an

experimental treatment, accessible only to a limited number of patients

and subject to rigid controls. No longer are patients required to have

attempted previous withdrawal treatments. Addiction can be ascertained by

spontaneous withdrawal attempts recounted during patients history.

Urinalysis is done only following doctor’s decision.

It is specified in our new guidelines that dosage and duration of

treatment should not be limited, but adapted to each patient by the

physician. It is acknowledged that short-term methadone treatment are

appropriate only in certain very particular cases. Daily administration of

methadone is not compulsory, but recommended at the beginning of treatment

and will generally take place in a pharmacy chosen by the patient. The

physician is free to prescribe larger quantities of methadone at less

frequent intervals, depending on how the patient evolves.

Conclusion

The number of heroin addicts undergoing methadone treatment is

increasing and now reaches 5.000, out of an estimated total number of

heroin users of 20.000 to 30.000. More than 80% of these patients are

being treated by general practitioners. Hundred of general practitioners

are currently involved in methadone treatment. Most patients receive

methadone provision for one or two weeks, but the presence of methadone on

the black market has decreased, since less addicts are seeking methadone

on the streets. Drug overdoses and criminality have decreased. Thus the

very flexible method of prescribing methadone used today in Belgium seems

to have resolved some problems and does not seem to have created

any.

Marc REISINGER
European Methadone Association
27 rue de la

Vanne
1050 Brussels, Belgium
Tel + Fax : 322 640 46 28


Notes

  1. Presented at the European Methadone Association Forum, AMTA Methadone Conference Phoenix, Arizona; October 31, 1995.

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