Drs. Vincent Dole and Marie Nyswander
Dr. Vincent Dole began his research career as a metabolic scientist with a speciality in obesity. He developed the first liquid dietary supplement and his work helped to change the public’s view that obese individuals get fat because they eat too much. He discovered that obese individuals metabolize food quite differently. He also came to realize that his obese patients were remarkably reminiscent of a narcotics addict’s craving for narcotics and so he decided to embark on a new area of research to study narcotic addiction.
Marie Nyswander was a psychiatrist, she was commissioned as a lieutenant in the navy during WW2 and assigned to the Public Health Service. Here she was sent to the hospital in Lexington, Kentucky that treated addiction. Upon leaving the Public Health Service she came to New York and continued to treat addicts, mostly free of charge out of her store front in “The Barrio”.
In the early 1960’s Dr. Dole embarked on his plan to study narcotic addiction. He found very little was known about the addict with the exception of one book written by Dr. Marie Nyswander called “The Addict as a Patient”. When Dr. Dole asked her to visit him to discuss the research he was considering Dr. Nyswander was beginning to realize that her efforts did not accomplish much and that perhaps maintaining addicts on narcotics might be the best solution. Of course Dr. Nyswander joined Dr. Dole’s research project which was the beginning of methadone treatment. (They would also fall in love and marry.) Dr. Dole brought the science to the project and Dr. Nyswander contributed the philosophy.
The two made a significant contributions to the field of addiction medicine which did not exist when they began their research project. These include: (1) developing the first effective treatment for opiate dependence, (2) bringing the treatment of addiction back to the medical profession, (3) postulating that addiction was a metabolic disease which led to the discovery of opiate receptors and endorphins (the first study looking for opiate receptors was done in Dr. Dole’s laboratory), (4) developing the first prison detoxification program, and also (5) developing urine screening for drugs (some call the test “The Dole Test”).
In the early Dole-Nyswander Program about half of the staff were patients that helped to significantly shape the philosophy of the early program. This was during a time when addicts were treated with disdain and some would say not much different than today. However, Drs. Dole and Nyswander thought of the patients that they treated as their peers, they brought the science and their patients brought their knowledge about addicts which together created an effective program.
The many contributions that they made to methadone treatment is not why NAMA is recognizing them. NAMA thinks that Drs. Dole and Nyswander are special and deserving of the title “Honorary Patient” because they cared about patients.
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